Iranian relations

I found this article, http://foxforum.blogs.foxnews.com/2009/04/22/alieza_iran_un/, by a foreign anylast discussing what the implications of further mismanagment of Iran could lead to. The anylast felt the Bush administration had done a horrible job with Relations of Iran and that it was up to Obama's administration to take a different route for relations. Clinton in this video, http://www.youtube.com/watch?v=a2sL_zITWJc, states that this change of policy is also needed, and that the administration is willing to speak with Iran about detering nuclear weapons and sanctions.
The journalist feels that some of the solution to the problem of nuclearization with Iran has to do with working with the people rather then just the leaders. He states there has been thousands of protests within Iran against the Islamic republic, and their is evidence of how upset the people are. It's also evident that the people of IRan are capable of making their concerns known and doing something about it, hence the revolution of 79, but it is difficult to see how the United States could aid this change. How can the oppresion of people by Religious Law be changed? How can the people of Iran bring about change in their country? If the United States changes its diplomacy efforts with Iran, in what ways could this bring about change for not just Iranian U.S. Relations but also regional relations, relations to the Islamic revivalist movenments among people in other countries, and also Israeli relations? Sorry this is a little off topic....